Vagus nerve stimulation for refractory idiopathic generalised epilepsy

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Vagus nerve stimulation for refractory idiopathic generalised epilepsy

We reviewed our experience with vagus nerve stimulation (VNS) in 165 patients with medically refractory epilepsy (138 partial epilepsy (PE), 13 symptomatic generalised epilepsy (SGE), 14 idiopathic generalised epilepsy (IGE)). Average duration of VNS therapy was 21.6 months. A 50% or greater reduction in seizure frequency was achieved in 47.1% of the PE group, 46.1% of the SGE group, and 57.1% ...

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Vagus nerve stimulation for refractory epilepsy

Vagus nerve stimulation (VNS) is a neurophysiological treatment for patients with medically or surgically refractory epilepsy. Since the first human implant in 1989, more than 10 000 patients have been treated with VNS. Two randomized controlled studies have shown a statistically significant decrease in seizure frequency during a 12-week treatment period versus a baseline period when 'high stim...

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Vagus Nerve Stimulation for Refractory Epilepsy

Context: Vagus nerve stimulation (VNS) is a relatively new treatment for epilepsy. Past studies have proposed that the antiepileptic action is related to the effect on the brainstem reticular activating system, and is mediated largely by the widespread release of two inhibitory agents (gamma aminobutyric acid [GABA] and glycine). Objective: To confirm the safety and efficacy of vagus nerve stim...

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Vagus nerve stimulation for medically refractory absence epilepsy

PURPOSE A proportion of patients with childhood and juvenile absence epilepsies (CAE, JAE) are likely to be classified as medically refractory. In view of evidence gap for the treatment of such patients, this series is reported to generate estimate for efficacy of vagus nerve stimulation (VNS) in this patient population. METHODS Patients were identified by a chart review of all VNS recipients...

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Cost-benefit of vagus nerve stimulation for refractory epilepsy.

PURPOSE Vagus nerve stimulation (VNS) is an established treatment for patients with medically refractory epilepsy who are unsuitable candidates for conventional epilepsy surgery. VNS requires an initial financial investment but apart from our own previous study there are no reports on cost-benefit published to date. The purpose of this paper is to assess prospectively the cost-benefit ratio of ...

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ژورنال

عنوان ژورنال: Seizure

سال: 2004

ISSN: 1059-1311

DOI: 10.1016/s1059-1311(03)00147-x